Human CHRNB3 HEK293 Overexpression Lysate MBS8115480 from MyBioSource.com

Description

Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence.

This Human CHRNB3 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of CHRNB3 protein from the overexpression lysate was verified

Product Specs
ItemHuman CHRNB3 HEK293 Overexpression Lysate
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS8115480
Format1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF
ApplicationsWestern Blot (WB)
Quantity0.3 mg
Molecular Weight52,729 Da
NCBI Full Gene Namecholinergic receptor nicotinic beta 3 subunit
Molecule NameCHRNB3
TypeOverexpression Lysate
Domain/Region/TerminusMet1-Leu232
Source/Expression SystemHEK293 Cells
Cell LineHEK293